Genotyping Using CGE-A Novel Single-Channel Microfluidic Device for Nucleic Acid Fragment Analysis

A Novel Single-Channel Microfluidic Device for Nucleic Acid Fragment Analysis

Nucleic acid analysis, genotyping, PCR, and RFLP methodologies are time-consuming techniques using agarose or acrylamide gel electrophoresis—image capture plus gel image interpretations. Capillary gel electrophoresis (CGE) automates these, providing fast separations with high sensitivity, excellent resolution, and ease of operation. However, despite its effectiveness current CGE has a high cost of instrumentation and cost per sample. Much of this cost is due to traditional designs.

BiOptics’ Qsep100™ CGE system solves this problem by integrating microcapillary electrophoretic technology into a plug-and-play disposable pen-shaped capillary gel cartridge with automated liquid handling, real time fluorescent detection, and analysis. Optimized for high resolution and high throughput at ambient temperatures, the need for expensive, extreme voltage power supplies and external cooling is eliminated, thus reducing instrument costs and increasing productivity.