CRISPR is a Genome Engineering technique that uses protein to interact with DNA. Genome editing begins with dsDNA cleavage. Cas9 is a dual-RNA-guided dsDNA endonuclease that is programmed by a single chimeric RNA. The guide RNA positions the Cas9 enzyme to the correct position on the target DNA for cleavage.
游離 DNA (circulating cell free DNA, cfDNA) 是指在細胞外呈現游離狀態無細胞保護的 DNA，廣泛存在於人類的血清、血漿、尿液等當中。尤其血液中的游離 DNA 更是現今蓬勃發展的「非侵入性檢測」技術的主要檢測標的。就產前醫學診斷來說，胎兒在母親懷孕期間，部分 DNA 會游離在母親血液當中，透過萃取母親體內的 cfDNA 可對胎兒進行非侵入性的產前診斷。
限制性片段長度多態性 Restriction Fragment Length Polymorphism (RFLP)此技術是於1984年英國科學家Alec Jeffreys在研究遺傳性疾病期間發展此技術，Jeffreys分析透過DNA序列重複之現象，證明遺傳性之關聯及個體差異，即為知名串聯重複 Variable Number of Tandem Repeats (VNTRs)，其發現此現象皆存在於所有人類身上但會因個體差異導致長度及重複的次數皆不相同。
Immunoassays are commonly used in biotechnology for the detection and quantification of host cell contaminants. The free-solution approach by CGE with fluorescence detection offers an exciting alternative to solid-phase immunoassay. It eliminates antigen immobilization and avoids many problems associated with solid phase. The methodology makes use of either a purified antigen labeled with stable fluorescent dye (i.e., FITC) or an affinity probe labeled with the dye (direct assay).
BiOptic Inc. introduces a cost-effective capillary gel-electrophoresis system for highly efficient, high speed, high throughput, Glycan analysis (N-Glycan). The Glycan Analyzer (GL1000) is a newly developed product that will significantly increase the pace at which glycoprotein research is performed in the lab, saving hours of preparation time and assuring accurate, consistent and economical results.
