Genomic DNA is the DNA that holds the complete set of genetic data for an organism. The term is used to distinguish this type of DNA from other kinds; although many people assume that all DNA is found in the genome, this is not, in fact, the case. Plasmids, for example, contain this genetic material, but this type is not part of the genome, even though it can be inherited and passed on to future generations.
The detailed study of genomic DNA is a topic of interest around the world, with a field of study known as bioinformatics being used to analyze and quantify data obtained through the study of various genomes. Researchers can do things like manipulating DNA to learn more about regulation and genome function, as well as creating genome databases that can be shared with other researchers. Collaboration can be key to solving genetic puzzles, because the vast size of the genome makes it logistically impossible for a single researcher to make much headway.
For genomic DNA research, BiOptic provides the Qsep100 to evaluate the quality of genomic DNA samples and precise genomic data analysis. The integrity of more than 1000 genomic DNA samples was evaluated by Qsep100 in order to evaluate the precision of subsequent qPRC analysis. By using the Qsep100 for the quality control of genomic DNA samples, the results show excellent reproducibility over the course of 1000 runs and was able to distinguish between the intact and degraded samples; therefore, it provided crucial information about which samples can be used for downstream qPCR processing.
Figure 1: The CGE fragment analysis on top is the DNA ladder with range from 75-2000 bps.
The rest of the analysis is comparing the intact gDNA with larger fragment size to degraded gDNA with smaller fragment size.