Qsep100^TM is a small, simple and user friendly bench top capillary gel electrophoresis (CGE) system integrated with a high sensitivity LED-induced fluorescence (LEDIF) detector with an easily-replaceable gel cartridge and 96-well auto-sampler. The 150 mm long capillary mounted into the cartridge contains a gel matrix that is replenished from the top reservoir of the cartridge automatically between sample runs. The reservoir provides sufficient gel for up to 200 sample injections providing robust and superior results for all kinds of molecular genetic analysis applications.