RNA analysis is used in numerous fields of scientific research. For example, virologists analyze RNA to assess disease etiology and geneticists use it to study gene expression in microarray assays. Like DNA, most biologically active RNAs, including mRNA, tRNA, rRNA, snRNAs, and other non-coding RNAs, contain self-complementary sequences that allow parts of the RNA to fold and pair with itself to form double helices. Analysis of these RNAs has revealed that they are highly structured. Unlike DNA, their structures do not consist of long double helices but rather collections of short helices packed together into structures akin to proteins. In this fashion, RNAs can achieve chemical catalysis, like enzymes. For instance, determination of the structure of the ribosome—an enzyme that catalyzes peptide bond formation—revealed that its active site is composed entirely of RNA
BiOptic produces the Qsep100 which offers valuable analytic insight in RNA-related research. Qsep100 can also be used in QC workflow during gene expression analyses such as qPCR and microarray analysis. Additionally, Qsep100 is able to perform quality control of total RNA.